For decades, women in perimenopause and menopause have been told that weight gain is inevitable. Hormone replacement therapy (HRT) helped improve hot flashes, sleep, and mood, but the scale often didn’t move. Meanwhile, GLP-1 receptor agonists, like semaglutide and tirzepatide, have made headlines for their powerful weight-loss results.

A growing body of research, including a 2024 study, suggests something important: when used together, HRT and GLP-1s may create greater weight loss benefits than either therapy alone.

This is where medical synergy comes in.

Let’s be honest. Losing your hair feels personal. You might notice it slowly, like your part is wider than it used to be, or all at once, like a handful of strands in the shower drain. Either way, it can be confusing, emotional, and frustrating when no one seems to take it seriously.